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Clinical Case Detail

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CPC Case IV
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Provided By
Yi-Ling Lin, DDS, DMSc andRussell Christensen, DDS - 2012-05-16
Clinical History
55 year old female with several month history of painful ulcers in the vestibule and buccal mucosa. Patient denies any significant medical history.

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Differential Diagnosis
  • Foreign material
  • Deep fungal infection
  • Tuberculosis
  • Crohn�fs disease
  • Sarcoidosis
  • Chronic granulomatous disease
Diagnosis
  • Crohn's Disease

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Clinical Features
  • Affect any portion of the GI tract
  • When fully developed, CD is characterized by skip lesions
    • sharp demarcation of diseased bowel segments from adjacent uninvolved bowel
  • Non-caseating granuloma in 40%-60% of cases
    • The absence of granulomas does not preclude a diagnosis of CD
  • Fissuring with formation of fistula
Radiographic Findings

Treatment & Prognosis

Discussion
Orofacial granulomatosis
  •  Clinical: nodular swelling, cobblestone appearance, deep ulcer
  • Not a specific diagnosis
References

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